Epstein–Barr virus latent membrane protein‐1 up‐regulates cytokines and correlates with older age and poorer prognosis in Hodgkin lymphoma
Histopathology2016Vol. 70(3), pp. 442–455
Citations Over TimeTop 19% of 2016 papers
Kung‐Chao Chang, Paul C‐H Chen, Yao Chang, Yu‐Hsuan Wu, Yaping Chen, Chien‐Hsien Lai, L. Jeffrey Medeiros, Ih‐Jen Su, Hsei–Wei Wang
Abstract
EBV infection appears to promote the release of cytokines in HL patients, and negatively impacts on patient survival. Physiological immunosenescence probably explains the association between EBV infection and older age. Cytokine modulation is a potential therapeutic target for EBV-positive HL patients.
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