Organisation of lymphocytic infiltrates in ANCA‐associated glomerulonephritis
Histopathology2018Vol. 72(7), pp. 1093–1101
Citations Over TimeTop 18% of 2018 papers
Silke R. Brix, Mercedes Noriega, Elisabeth M Herden, Birgit Goldmann, Ulrike Langbehn, Martin Busch, Wolfram J. Jabs, Oliver M. Steinmetz, Ulf Panzer, Tobias B. Huber, Rolf A.K. Stahl, Thorsten Wiech
Abstract
In the present study, we show that the renal lymphocytic organisation is associated with renal outcome in ANCA-associated GN. The organisation of the lymphocytic infiltrate may be a morphological correlate of a perpetual and exaggerated inflammation in renal ANCA disease. Classifying the lymphocytic infiltrate could help to predict renal outcome, and might therefore be used for individualised adjustments in the intensity and duration of immunosuppressive therapy.
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