BRCA1 and BRCA2 carriers with breast, ovarian and prostate cancer demonstrate a different pattern of metastatic disease compared with non‐carriers: results from a rapid autopsy programme
Histopathology2023Vol. 83(1), pp. 91–103
Citations Over TimeTop 13% of 2023 papers
Heather Thorne, Lisa Devereux, Jason Li, Kathryn Alsop, Liz Christie, Courtney T. van Geelen, Nikki Burdett, Kathleen I. Pishas, Noel Woodford, Jodie Leditschke, Mohamed H M A Izzath, Kate Strachan, Greg Young, Rufaro Diana Jaravaza, Mohammed Madadin, Melanie S. Archer, Joanna Glengarry, Linda Iles, Ajith Rathnaweera, Clare Hampson, Khamis Almazrooei, Michael Burke, Pradeep Bandara, David Ranson, Essa Saeedi, Orla McNally, Linda Mileshkin, Anne Hamilton, Sumitra Ananda, George Au‐Yeung, Yoland Antill, Shahneen Sandhu, Peter Savas, Prudence A. Francis, Stephen Luen, Sherene Loi, Ross Jennens, Clare L. Scott, Kate Moodie, Margaret C. Cummings, Andrew Reid, Amy E. McCart Reed, David D.L. Bowtell, Sunil R. Lakhani, Stephen B. Fox
Abstract
Even though a major limitation of this study is that our numbers are small, especially in the breast cancer carrier group, the metastatic patterns of breast and ovarian cancers may be impacted by BRCA1/2 carrier status, suggesting that tumours derived from patients with these mutations use different mechanisms of dissemination. The findings may focus clinical diagnostic imaging for monitoring metastases where whole-body imaging resources are scant.
Related Papers
- → Introduction of autopsy imaging redefines the concept of autopsy: 37 cases of clinical experience(2003)57 cited
- Correlation between ultrasound diagnosis and autopsy findings of fetal malformations.(2012)
- → The Role of Postmortem Computed Tomography in the Evaluation of Strangulation Deaths(2018)25 cited
- → Autopsy Utilization in Medicolegal Defense of Anesthesiologists(2011)14 cited
- Pathological study on 18 cases of forensic re-autopsy and histopathological re-examination(2001)