A new ex vivo human skin model for the topographic and biological analysis of cosmetic formulas
International Journal of Cosmetic Science2024Vol. 47(2), pp. 305–320
Citations Over TimeTop 19% of 2024 papers
Laurent Peno‐Mazzarino, Olivier Jeanneton, S. Almeida Scalvino, Giuseppe Percoco, Gallic Beauchef, Carine Nizard, Karl Pays
Abstract
The Perfex setup allows for similar preservation of skin explant histology and key protein expression as the conventional system, yet it maintains a skin surface close to that of in vivo skin. Therefore, it is valuable to analyse both the short- and mid- to long-term impacts of skin care formulas and better comprehend their effects. The Perfex system also offers a new tool for investigating fundamental questions, such as the link that can exist between dermal proteins and skin surface properties.
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