Rationale, Design, and Progress of the ENhanced Control of Hypertension ANd Thrombolysis Stroke Study (ENCHANTED) Trial: An International Multicenter 2 × 2 Quasi-Factorial Randomized Controlled Trial of Low- vs. Standard-Dose rt-PA and Early Intensive vs. Guideline-Recommended Blood Pressure Lowering in Patients with Acute Ischaemic Stroke Eligible for Thrombolysis Treatment
International Journal of Stroke2015Vol. 10(5), pp. 778–788
Citations Over TimeTop 10% of 2015 papers
Yining Huang, Vijay K. Sharma, Thompson Robinson, Richard I. Lindley, Xiaoying Chen, Jong Sung Kim, Pablo M. Lavados, Verónica V. Olavarría, Hisatomi Arima, Sully Fuentes, Huy Thang Nguyen, Tsong‐Hai Lee, Mark Parsons, Christopher Levi, Andrew M. Demchuk, Philip M. Bath, Joseph P. Broderick, Geoffrey A. Donnan, Sheila Cristina Ouriques Martins, Octávio Marques Pontes‐Neto, Federico Silva, Jeyaraj Pandian, Stefano Ricci, Christian Stapf, Mark Woodward, Ji‐Guang Wang, John Chalmers, Craig S. Anderson, for the ENCHANTED investigators
Abstract
Low-dose i.v. rt-PA and early intensive BP lowering could provide more affordable and safer use of thrombolysis treatment for patients with AIS worldwide.
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