MicroRNA signatures characterizing caste‐independent ovarian activity in queen and worker honeybees ( A pis mellifera L.)

Citations Over TimeTop 10% of 2016 papers

Abstract

Abstract Queen and worker honeybees differ profoundly in reproductive capacity. The queen of this complex society, with 200 highly active ovarioles in each ovary, is the fertile caste, whereas the workers have approximately 20 ovarioles as a result of receiving a different diet during larval development. In a regular queenright colony, the workers have inactive ovaries and do not reproduce. However, if the queen is sensed to be absent, some of the workers activate their ovaries, producing viable haploid eggs that develop into males. Here, a deep‐sequenced ovary transcriptome library of reproductive workers was used as supporting data to assess the dynamic expression of the regulatory molecules and microRNAs (miRNAs) of reproductive and nonreproductive honeybee females. In this library, most of the differentially expressed miRNAs are related to ovary physiology or oogenesis. When we quantified the dynamic expression of 19 miRNAs in the active and inactive worker ovaries and compared their expression in the ovaries of virgin and mated queens, we noted that some miRNAs ( miR‐1, miR‐31a, miR‐13b, miR‐125, let‐7 RNA, miR‐100, miR‐276, miR‐12, miR‐263a, miR‐306, miR‐317, miR‐92a and miR‐9a ) could be used to identify reproductive and nonreproductive statuses independent of caste. Furthermore, integrative gene networks suggested that some candidate miRNAs function in the process of ovary activation in worker bees.

Related Papers

• → Hartnell, Sir Norman, (12 June 1901–8 June 1979), Dressmaker by appointment to HM the Queen, and to HM Queen Elizabeth the Queen Mother; Member Incorporated Society of London Fashion Designers (Chairman 1947–56); Ex-Vice-President Clothing Institute(2007)1 cited
• → Gordon, Lord Adam (Granville), (1 March 1909–5 July 1984), Comptroller to Queen Elizabeth the Queen Mother, 1953–73; Extra Equerry to Queen Elizabeth the Queen Mother, since 1974(2007)
• → Queen Elizabeth: real persons in “the Faerie Queen”(1871)
• → Seymour, Lady Katharine, (25 Feb. 1900–28 April 1985), Extra Woman of the Bedchamber to Queen Elizabeth the Queen Mother since 1960 (Woman of the Bedchamber to the Queen (now Queen Elizabeth the Queen Mother), 1937–60); First Woman of the Bedchamber to Queen Mary, 1927–30 (on marriage became Extra Woman of the Bedchamber, 1930–53)(2007)
• アメリカ便り(24)ニューヨーク港を訪れる海の女王たち--Queen Victoria, Queen Mary 2, Queen Elizabeth 2, Queen Elizabeth, Queen Mary(2008)