Microsatellite and chromosomal stable colorectal cancers demonstrate poor immunogenicity and early disease recurrence
Colorectal Disease2008Vol. 11(6), pp. 601–608
Citations Over TimeTop 12% of 2008 papers
Abstract
Stratification of colorectal cancer by MSI and ploidy status may have prognostic value in patients undergoing curative surgery. MSI-H cancers display enhanced immunogenic properties but the immune response to MACS cancers appears to be absent and this may contribute to their poor prognosis.
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