Antipsychotic withdrawal symptoms: Phenomenology and pathophysiology
Acta Psychiatrica Scandinavica1988Vol. 77(3), pp. 241–246
Citations Over TimeTop 10% of 1988 papers
Abstract
The authors review the literature discribing non-dyskinetic antipsychotic withdrawal phenomena. Withdrawal of these agents can cause nausea, emesis, anorexia, diarrhea, rhinorrhea, diaphoresis, myalgia, paresthesia, anxiety, agitation, restlessness, and insomnia. Psychotic relapse is often presaged by increased anxiety, agitation, restlessness and insomnia, but the temporal relationship of these prodromal symptoms to reduction in the dosage or discontinuation of neuroleptics distinguishes them from the effects of abrupt withdrawal.
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