The combination of type I interferon and ribavirin has an inhibitory effect on mouse hepatitis virus infection
Hepatology Research2007Vol. 37(2), pp. 121–126
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Abstract
These data indicate that this MHV-infection system is a good animal model to assess anti-HCV activity for therapy using IFN and ribavirin, and suggest that administering IFN-beta before the start of combination therapy with ribavirin and IFN-alpha promotes the therapeutic effects of combination treatment with ribavirin and IFN-alpha ?in chronic hepatitis C patients.
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