Stability of Rotors and Focal Sources for Human Atrial Fibrillation: Focal Impulse and Rotor Mapping (FIRM) of AF Sources and Fibrillatory Conduction
Journal of Cardiovascular Electrophysiology2014Vol. 25(12), pp. 1284–1292
Citations Over TimeTop 10% of 2014 papers
Vijay Swarup, Tina Baykaner, Armand Rostamian, James P. Daubert, John D. Hummel, David E. Krummen, Rishi Trikha, John M. Miller, Gery Tomassoni, Sanjiv M. Narayan
Abstract
Rotors and focal sources for human AF mapped by FIRM over prolonged time periods precess ("wobble") but remain within stable regions for thousands of cycles. Conversely, emanating activity such as spiral waves disorganize and collide with the fibrillatory milieu, explaining difficulties in using activation mapping or signal processing analyses at fixed electrodes to detect AF rotors. These results provide a rationale for targeted ablation at AF sources rather than fibrillatory spiral waves.
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