Effect of Irrigant Characteristics on Lesion Formation After Radiofrequency Energy Delivery Using Ablation Catheters with Actively Cooled Tips

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Abstract

In ex vivo and in vivo models, decreased osmolarity and charge density increased RF energy delivery to tissue, resulting in larger lesions for both open and closed irrigated ablations. A perpendicular catheter position created larger lesions across all irrigants for both open and closed irrigation ablation. The incidence of steam pops was observed more frequently with high power open irrigated using D5W, especially if the catheter was in a perpendicular position. Further research is required to evaluate any clinical role for using different irrigants with an externally irrigated catheter.

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