Safety and chronic lesion characterization of pulsed field ablation in a Porcine model
Journal of Cardiovascular Electrophysiology2021Vol. 32(4), pp. 958–969
Citations Over TimeTop 1% of 2021 papers
Mark T. Stewart, David E. Haines, Damijan Miklavčič, Bor Kos, Nicole Kirchhof, Noah Barka, Lars M. Mattison, Matt Martien, Birce Önal, Brian Howard, Atul Verma
Abstract
PFA deliveries to the SVC, RAA, and RSPV resulted in complete circumferential replacement fibrosis at 4-week postablation with an excellent chronic myocardial and collateral tissue safety profile. This GLP study evaluated the safety and efficacy of a dosage range in preparation for a clinical trial and characterized the non-thermal nature of PFA.
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