Development of a clinically relevant ex vivo model of cardiac ablation for testing of ablation catheters
Journal of Cardiovascular Electrophysiology2022Vol. 34(3), pp. 682–692
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Christopher S. Lacko, Qi Chen, Vivienne Mendoza, Vanessa Parikh, Gary Eichenbaum, Meir Bar‐Tal, Chad E. Eckert, Héctor De León, John P. Matonick, Tushar Sharma
Abstract
The ex vivo model exhibited strong lesion reproducibility and power-to-depth ratios comparable to the in vivo TP model. The optimized ex vivo model minimizes animal usage with increased throughput, lesion characteristics similar to the in vivo TP model, and ability to discriminate minor variations between different catheter designs.
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