Annual Research Review: The (epi)genetics of neurodevelopmental disorders in the era of whole‐genome sequencing – unveiling the dark matter
Journal of Child Psychology and Psychiatry2015Vol. 56(3), pp. 278–295
Citations Over TimeTop 10% of 2015 papers
Abstract
In this overview, we discuss a backbone continuum concept of NDDs by summarizing pertinent findings in genetics and epigenetics. We also provide an appraisal of the genetic overlap versus differences, with a focus on genome-wide screening approaches for (epi)genetic variation. Finally, we conclude with insights from evolutionary psychobiology suggesting positive selection for discrete NDD-associated traits.
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