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A network approach to the investigation of childhood irritability: probing frustration using social stimuli
Journal of Child Psychology and Psychiatry2023Vol. 65(7), pp. 959–972
Khalil Thompson, Clayton J. Schneider, Justin A. Lopez‐Roque, Lauren S. Wakschlag, Helmet T. Karim, Susan B. Perlman
Abstract
Our findings point to specific neural circuitry underlying pediatric irritability in the context of frustration using social stimuli. Results suggest that a deliberate focus on the construction of network-based neurodevelopmental profiles and social interaction along the normal:abnormal irritability spectrum is warranted to further identify comprehensive transdiagnostic substrates of the irritability.
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