Are sleep studies helpful in children with Prader–Willi syndrome prior to commencement of growth hormone therapy?

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Abstract

OSA was frequently present in children with PWS referred simply to meet the requirement for PSG before starting GH. OSA was more likely in older children and those with enlarged tonsils. GH treatment was deferred in 38% of cases. This study supports routine performance of PSG prior to GH, regardless of clinical history.

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