Lipophilicity and hydrophobicity considerations in bio-enabling oral formulations approaches – a PEARRL review
Journal of Pharmacy and Pharmacology2018Vol. 71(4), pp. 464–482
Citations Over TimeTop 10% of 2018 papers
Felix Ditzinger, Daniel J. Price, Alexandra-Roxana Ilie, Niklas J Köhl, Sandra Janković, Γεωργία Τσακιρίδου, Simone Aleandri, Lida Kalantzi, René Holm, Anita Nair, Christoph Saal, Brendan T. Griffin, Martin Kuentz
Abstract
Current literature suggests that selection of formulation approaches in pharmaceutics is still highly dependent on the availability of technological expertise in a company or research group. Encouraging is that, recent advancements point to more structured and scientifically based development approaches. More research is still needed to better link physicochemical drug properties to pharmaceutical formulation design.
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