Demonstrating suitability of the Caco-2 cell model for BCS-based biowaiver according to the recent FDA and ICH harmonised guidelines
Journal of Pharmacy and Pharmacology2019Vol. 71(8), pp. 1231–1242
Citations Over TimeTop 12% of 2019 papers
Abstract
Assay standardisation assures the consistency of experimental data. Only such fully characterised model has the ability to accurately predict drug's intestinal permeability at the early stage of research or for the BCS-based biowaiver application.
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