Super‐resolution microscopy as a potential approach to diagnosis of platelet granule disorders
Journal of Thrombosis and Haemostasis2016Vol. 14(4), pp. 839–849
Citations Over TimeTop 10% of 2016 papers
D. Westmoreland, Michael Shaw, William N. Grimes, Daniel Metcalf, Jemima J. Burden, Keith Gomez, Alex E. Knight, Daniel F. Cutler
Abstract
A super-resolution imaging approach is effective and rapid in objectively differentiating between patients with a platelet bleeding disorder and healthy volunteers. CD63 is a useful marker for predicting Hermansky-Pudlak syndrome and could be used in the diagnosis of patients suspected of other platelet granule disorders.
Related Papers
- → The protein CD63 is in platelet dense granules, is deficient in a patient with Hermansky-Pudlak syndrome, and appears identical to granulophysin.(1993)148 cited
- → Flow cytometric analysis of platelet function in stored platelet concentrates(1999)61 cited
- Effects of normal and aspirin platelets on defective secondary aggregation in the Hermansky-Pudlak syndrome. A test for storage pool deficient platelets.(1972)
- → Relationship Between Mepacrine-Labelled Dense Body Number, Platelet Capacity to Accumulate 14C-5-HT and Platelet Density in the Bernard-Soulier and Hermansky-Pudlak Syndromes(1979)45 cited
- → Golgi complexes in hypogranular platelet syndromes(2004)8 cited