Pharmacological thromboprophylaxis to prevent venous thromboembolism in patients with temporary lower limb immobilization after injury: systematic review and network meta‐analysis
Journal of Thrombosis and Haemostasis2019Vol. 18(2), pp. 422–438
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Daniel Horner, John Stevens, Abdullah Pandor, Tim Nokes, Jonathan Keenan, Kerstin de Wit, Steve Goodacre
Abstract
Thromboprophylaxis with either fondaparinux or LMWH appears to reduce the odds of both asymptomatic and clinically detected VTE in people with temporary lower limb immobilization following an injury. Treatment effects vary by outcome and are not always conclusive. We were unable to identify any treatment effect modifiers other than thromboprophylactic agent used.
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