The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second‐generation subtypes
Neuropathology and Applied Neurobiology2020Vol. 47(2), pp. 236–250
Citations Over TimeTop 17% of 2020 papers
Debbie Hicks, Gholamreza Rafiee, Ed C. Schwalbe, C. I. Howell, Janet C. Lindsey, Robert M. Hill, Amanda Smith, Peter Adidharma, Catherine Steel, Sarah J. Richardson, Lori J. Pease, Marina Danilenko, S Crosier, Abhijit Joshi, Stephen B. Wharton, Thomas S. Jacques, Barry Pizer, A. Michalski, Daniel Williamson, Simon Bailey, Steven C. Clifford
Abstract
Investigations of large, retrospective cohorts have enabled the comprehensive and robust characterization of molecular heterogeneity within iMB. Novel subtypes are clinically significant and subgroup-dependent survival models highlight opportunities for biomarker-directed therapies.
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