The hypersensitivity to colonic distension of IBS patients can be transferred to rats through their fecal microbiota
Neurogastroenterology & Motility2013Vol. 25(4), pp. e272–82
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Laureen Crouzet, E. Gaultier, Christophe Del’Homme, C. Cartier, Eve Delmas, Michel Dapoigny, Jean Fioramonti, Annick Bernalier‐Donadille
Abstract
We herein showed that sensitivity to colonic distension of IBS patients can be transferred to rats by the fecal microbiota. Mucosal alterations associated with microbiota transfer are not involved in this hypersensitivity. The altered IBS microbiota may have important role in the hypersensitivity characterizing IBS patients through specific bacterial metabolites.
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