Anal sphincter fatigability in assessing anal incontinence: A systematic review
Neurogastroenterology & Motility2022Vol. 34(9), pp. e14342–e14342
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Dakshitha Praneeth Wickramasinghe, Nilanka Wickramasinghe, Sohan Anjana Kamburugamuwa, Dharmabandhu Nandadeva Samarasekera, Janindra Warusavitarne, C. J. Vaizey
Abstract
Sphincter fatigability, measured by the Fatigability Rate Index, has good discriminating power for anal incontinence. A standardized protocol needs to be followed by future researchers. Graphical Abstract The analysis used six studies with 413 patients to compare Fatigue Rate Index between patients with AI and controls. All studies reported a lower FRI in patients with incontinence and the FRI was significantly lower in patients with AI (standardized mean difference [SMD] 1.636, p= 0.001). Conflicting results were reported on the correlation between FRI and AI symptom scores.
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