Function of gold nanoparticles in oral cancer beyond drug delivery: Implications in cell apoptosis
Oral Diseases2020Vol. 27(2), pp. 251–265
Citations Over TimeTop 10% of 2020 papers
Marwa M. Essawy, Sahar M. El‐Sheikh, Hanaa Raslan, Heba Ramadan, Bin Kang, Iman M. Talaat, Marwa M. Afifi
Abstract
Our findings suggest that AuNPs enhance the cytotoxic effect against cancer cells in addition to acting as drug carriers. DOX pH-resistant AuNPs enhanced accumulation of AuNPs in cancer cells' nuclei inducing a significant cellular apoptosis which was confirmed using in vitro and in vivo experiments without deleterious effects on blood cell count.
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