Associations between child filaggrin mutations and maternal diet with the development of allergic diseases in children
Pediatric Allergy and Immunology2022Vol. 33(3), pp. e13753–e13753
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Carina Venter, Michaela P. Palumbo, Katherine A. Sauder, Deborah H. Glueck, Liam O’Mahony, Ivana V. Yang, Elizabeth Davidson, Helen A. Brough, John W. Holloway, David M. Fleischer, Miriam Ben‐Abdallah, Dana Dabelea
Abstract
Children with FLG mutation had similar risk of atopic dermatitis, asthma, and wheeze as children without an FLG mutation whose mothers did not eat an allergy preventive diet during pregnancy. Child FLG mutation did not modify the effect of maternal diet. The results suggest that maternal diet in pregnancy, a modifiable risk factor, could be a target for preventive interventions.
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