Multi‐ancestry genome‐wide association study of asthma exacerbations
Pediatric Allergy and Immunology2022Vol. 33(6), pp. e13802–e13802
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Esther Herrera‐Luis, Victor E. Ortega, Elizabeth J. Ampleford, Yang Yie Sio, Raquel Granell, Emmely W. de Roos, Natalie Terzikhan, Ernesto Elorduy Vergara, Natalia Hernandez‐Pacheco, Javier Pérez-García, Elena Martín-González, Fabián Lorenzo-Díaz, Simone Hashimoto, Paul Brinkman, U‐BIOPRED Study Group, Andrea Jorgensen, Qi Yan, Erick Forno, Susanne J. H. Vijverberg, Ryan Lethem, Antonio Espuela‐Ortiz, Mario Gorenjak, Celeste Eng, Ruperto González‐Pérez, José María Hernández Pérez, Paloma Poza‐Guedes, Olaia Sardón‐Prado, Paula Corcuera, Greg Hawkins, Annalisa Marsico, Thomas Bahmer, Klaus F. Rabe, Gesine Hansen, Matthias Kopp, Raimon Rios, María Jesús Cruz, Francisco Javier González‐Barcala, José M. Rivera, Vicente Plaza, Santiago Quirce, Glorisa Canino, Michelle M. Cloutier, Victoria del Pozo, José Rodríguez‐Santana, Javier Korta‐Murua, Jesús Villar, Uroš Potočnik, Camila Alexandrina Figueiredo, Michael Kabesch, Somnath Mukhopadhyay, Munir Pirmohamed, Daniel B. Hawcutt, Erik Melén, Colin N. Palmer, Steve Turner, Anke H. Maitland‐van der Zee, Erika von Mutius, Juan C. Celedón, Guy Brusselle, Fook Tim Chew, Eugene R. Bleecker, Deborah A. Meyers, Esteban G. Burchard, Maria Pino‐Yanes
Abstract
This multi-ancestry study revealed novel suggestive regulatory loci for asthma exacerbations located in genomic regions participating in inflammation and host defense.
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