β‐cell function, incretin response, and insulin sensitivity of glucose and fat metabolism in obese youth: Relationship to OGTT‐time‐to‐glucose‐peak
Pediatric Diabetes2019Vol. 21(1), pp. 18–27
Citations Over TimeTop 14% of 2019 papers
Joon Young Kim, Hala Tfayli, Fida Bacha, SoJung Lee, Sara F. Michaliszyn, Shahwar Yousuf, Nour Y. Gebara, Silva Arslanian
Abstract
In obese non-diabetic youth, those with a Late-peak vs an Early-peak glucose during an OGTT showed diminished β-cell function, blunted incretin secretion, and lower insulin sensitivity of glucose and FFA metabolism. It remains to be determined if Late-peak glucose predicts the future development of type 2 diabetes in these high-risk youth.
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