Blood removal therapy in hereditary hemochromatosis induces a stress response resulting in improved genome integrity
Transfusion2016Vol. 56(6), pp. 1435–1441
Citations Over Time
S Distante, Joakim Eikeland, Tina Pawar, Ragnhild Skinnes, Kari Høie, Panpan You, Lars Mørkrid, Lars Eide
Abstract
We conclude that phlebotomy therapy in HH does not merely restore systemic iron homeostasis, but induces an "oxidative stress" defense response that manifests as improved genome integrity. These findings provide novel insights into an ancient therapy.
Related Papers
- [Arthropathy in hemochromatosis].(1993)
- → Some patients with hereditary hemochromatosis do not require chronic therapeutic phlebotomy(2001)
- → Hemochromatosis(1992)
- → Some patients with hereditary hemochromatosis do not require chronic therapeutic phlebotomy(2001)
- [Hereditary hemochromatosis: molecular diagnosis and effect of treatment].(2004)