Noninvasive fetal genotyping of paternally inherited alleles using targeted massively parallel sequencing in parentage testing cases
Transfusion2017Vol. 57(6), pp. 1505–1514
Citations Over TimeTop 10% of 2017 papers
Donggui Yang, Hao Liang, Yu Gao, Shaobin Lin, Zhiming He, Jun Gao, Hongyu Sun, Qing Li, Xiaoyan Ma, Xueling Ou
Abstract
In our study, we evaluate a straightforward method that can be used to identify paternal alleles based on analyses of paternal alleles and sequencing errors in maternal plasma. Our results support the notion that an MPS-based method could be utilized in noninvasive fetal genotyping and prenatal paternity analyses.
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