Development of a recombinant anti‐Vel immunoglobulin M to identify Vel‐negative donors
Transfusion2019Vol. 59(4), pp. 1359–1366
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Marea V.E. van der Rijst, Suzanne N. Lissenberg‐Thunnissen, Peter C. Ligthart, Remco Visser, J.M. Jongerius, Lesley Voorn, Barbera Veldhuisen, Gestur Vidarsson, Emile van den Akker, C. Ellen van der Schoot
Abstract
We generated a directly agglutinating recombinant anti-Vel IgM, M3F5S-IgM, functional in manual, automated agglutination assays and flow cytometry settings. This IgM anti-Vel will improve diagnostics by facilitating the identification of Vel-negative blood donors.
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