Antibodies against biotin‐labeled red blood cells can shorten posttransfusion survival
Transfusion2022Vol. 62(4), pp. 770–782
Citations Over TimeTop 14% of 2022 papers
Donald M. Mock, Sean R. Stowell, Robert S. Franco, Svetlana V. Kyosseva, Demet Nalbant, Robert L. Schmidt, Gretchen A. Cress, Ronald G. Strauss, José A. Cancelas, Melissa von Goetz, Anne North, John A. Widness
Abstract
We conclude re-exposure of immunized subjects to BioRBC can induce anamnestic antibody response that can cause an underestimation of RCS. To minimize chances of antibody induction and underestimation of RCS, we recommend an initial BioRBC exposure volume of ≤10 mL and label densities of ≤18 μg/mL.
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