Hypothermic machine perfusion of kidneys retrieved from standard and high-risk donors
Citations Over TimeTop 10% of 2015 papers
Abstract
Hypothermic machine perfusion (HMP) of kidneys is a long-established alternative to static cold storage and has been suggested to be a better preservation method. Today, as our deceased donor profile continues to change towards higher-risk kidneys of lower quality, we are confronted with the limits of cold storage. Interest in HMP as a preservation technique is on the rise. Furthermore, HMP also creates a window of opportunity during which to assess the viability and quality of the graft before transplantation. The technology might also provide a platform during which the graft could be actively repaired, making it particularly attractive for higher-risk kidneys. We review the current evidence on HMP in kidney transplantation and provide an outlook for the use of the technology in the years to come.
Related Papers
- → Hypothermic machine perfusion in liver transplantation(2016)80 cited
- → One or 4 h of “in-house” reconditioning by machine perfusion after cold storage improve reperfusion parameters in porcine kidneys(2014)37 cited
- THE EFFECT OF THE CD 68 AND CRP IN THE ISOLATED LIVER BETWEEN STATIC COLD STORAGE AND HYPOTHERMIC MACHINE PERFUSION BEFORE AND AFTER LIVER TRANSPLANTATION(2015)
- → Machine Perfusion of Human Donor Livers(2020)
- → P11.41: Investigation of Optimal Temperature for Machine Perfusion of Liver Transplantation in Donors After Cardiac Death(2022)