Delayed type III hypersensitivity reaction with acute kidney injury in two dogs following administration of concentrated human albumin during treatment for hypoalbuminemia secondary to septic peritonitis
Journal of Veterinary Emergency and Critical Care2020Vol. 30(5), pp. 574–580
Citations Over TimeTop 17% of 2020 papers
Elisa M. Mazzaferro, Anusha Balakrishnan, Susan G. Hackner, Marnin Forman, J.F. Foster, Janine M. Calabro, Rachel E. Cianciolo
Abstract
Severe type III hypersensitivity reactions have been documented in healthy dogs and clinical patients following the administration of HSA. This report describes the first documented delayed type III hypersensitivity reaction in 2 dogs with septic peritonitis that resulted in AKI, glomerulonephritis, and oligo- to anuria in clinical patients following administration of 25% HSA.
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