Alterations in default network connectivity in posttraumatic stress disorder related to early-life trauma
Journal of Psychiatry and Neuroscience2009Vol. 34(3), pp. 187–194
Citations Over TimeTop 10% of 2009 papers
Robyn Bluhm, Peter Williamson, Elizabeth Osuch, Paul Frewen, Todd K. Stevens, Kristine Boksman, Richard W. J. Neufeld, Jean Théberge, Ruth A. Lanius
Abstract
Spontaneous activity in the default network during rest, as measured using PCC correlations, is altered in patients with PTSD. The potential effects of psychotropic medications on default network connectivity in the present sample remain unknown. In this patient population, the observed alterations may be associated with the disturbances in self-referential processing often observed in patients with chronic PTSD related to early-life trauma.
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