The mTOR Pathway in the Control of Protein Synthesis
Physiology2006Vol. 21(5), pp. 362–369
Citations Over TimeTop 1% of 2006 papers
Abstract
Signaling through mammalian target of rapamycin (mTOR) is activated by amino acids, insulin, and growth factors, and impaired by nutrient or energy deficiency. mTOR plays key roles in cell physiology. mTOR regulates numerous components involved in protein synthesis, including initiation and elongation factors, and the biogenesis of ribosomes themselves.
Related Papers
- → Targeting mTOR globally in cancer: Thinking beyond rapamycin(2009)155 cited
- → Chapter 11 Monitoring Mammalian Target of Rapamycin (mTOR) Activity(2009)61 cited
- → Evaluating the mTOR Pathway in Physiological and Pharmacological Settings(2016)7 cited
- → mTOR signaling in liver disease(2015)2 cited
- → Regulation and function of the TSC‐mTOR pathway in cell growth(2008)