Increased IgE Deposition in Appendicular Tissue Specimens Is Compatible with a Type I Hypersensitivity Reaction in Acute Appendicitis
Mediators of Inflammation2021Vol. 2021(1), pp. 4194859–4194859
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Nuno Carvalho, André Barros, Hélder Coelho, Ana Cóias, Pedro Botelho, Brigitta Cismasiu, Luís F. Moita, Paulo Costa
Abstract
In this study, phlegmonous appendicitis had the highest number of IgE-positive appendicular cells. These findings suggest that an allergic reaction can contribute to the pathophysiology of AA, opening a novel possibility for preventive measures in a disease that typically requires surgery.
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