Methylation Markers for CCNA1 and C13ORF18 Are Strongly Associated with High-Grade Cervical Intraepithelial Neoplasia and Cervical Cancer in Cervical Scrapings
Cancer Epidemiology Biomarkers & Prevention2009Vol. 18(11), pp. 3000–3007
Citations Over TimeTop 13% of 2009 papers
Nan Yang, Jasper J.H. Eijsink, Ágnes Lendvai, Haukeline H. Volders, Harry Klip, Henk J. Buikema, Bettien M. van Hemel, Ed Schuuring, Ate G.J. van der Zee, G. Bea A. Wisman
Abstract
Methylation of CCNA1 and C13ORF18 in cervical scrapings is strongly associated with CIN II or higher-grade lesions. Therefore, these markers might be used for direct referral to gynecologists for patients with a methylation-positive scraping.
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