Novel Glioblastoma Markers with Diagnostic and Prognostic Value Identified through Transcriptome Analysis
Clinical Cancer Research2008Vol. 14(10), pp. 2978–2987
Citations Over TimeTop 10% of 2008 papers
Sreekanth P. Reddy, Ramona Britto, Katyayni Vinnakota, Hebbar Aparna, Hari Kishore Sreepathi, Balaram Thota, Arpana Kumari, B.M. Shilpa, Marigowda Vrinda, Umesh Srikantha, Cini Samuel, Mitesh Shetty, Ashwani Tandon, Paritosh Pandey, Sridevi Hegde, Atmananda Hegde, Anandh Balasubramaniam, Bangalore A. Chandramouli, Vani Santosh, Paturu Kondaiah, Kumaravel Somasundaram, Manchanahalli R. Satyanarayana Rao
Abstract
Our study reveals that GADD45alpha and FSTLI are GBM-specific whereas superoxide dismutase 2 and adipocyte enhancer binding protein 1 are primary GBM-specific diagnostic markers. Whereas GADD45alpha overexpression confers a favorable prognosis, FSTL1 overexpression is a hallmark of poor prognosis in GBM patients.
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