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Prurigo nodularis Consists of Two Distinct Forms: Early-Onset Atopic and Late-Onset Non-Atopic
Dermatology1995Vol. 190(4), pp. 269–276
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Abstract
These results indicate that there are two forms of PN: an atopic and a non-atopic one. The PN+AD group is closely associated with AD, being accompanied by cutaneous hypersensitivity to various environmental allergens (a pattern similar to that displayed by AD patients) and has a younger age of onset, whereas the PN-only group, which showed a much older age of onset, does not show any such hypersensitive reactions against these allergens.
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