Carboplatin Dosing in Children: Calculation by Different Formulae
Oncology Research and Treatment2011Vol. 34(1-2), pp. 16–22
Citations Over Time
Abstract
The choice of the GFR formula is more important for the carboplatin dose calculation compared to the BSA or dose equation. GFR calculations in children show marked, age-dependent variations. A sequence of multiple calculation steps (especially for the Schwartz and Marina formulae) may lead to considerable uncertainty and proneness to error in the clinical routine. In high-risk patients, GFR should be measured precisely and complemented by therapeutic drug monitoring.
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