Snail Driving Alternative Splicing of CD44 by ESRP1 Enhances Invasion and Migration in Epithelial Ovarian Cancer
Cellular Physiology and Biochemistry2017Vol. 43(6), pp. 2489–2504
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Le Chen, Ying Yao, Lijuan Sun, Jiajia Zhou, Minmin Miao, Shujuan Luo, Guanming Deng, Junjun Li, Jing Wang, Jie Tang
Abstract
ESRP1 regulates CD44 alternative splicing during the EMT process which plays an important role in EOC carcinogenesis. In addition, ESRP1 is associated with disease prognosis in EOC.
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