Anti-Cancer Effects of Radix Angelica Sinensis (Danggui) and N-Butylidenephthalide on Gastric Cancer: Implications for REDD1 Activation and mTOR Inhibition

Citations Over TimeTop 10% of 2018 papers

Abstract

Danggui can prolong the survival rate of gastric cancer patients in Taiwan. BP caused gastric cancer cell death through the activation of mitochondria-intrinsic pathway and induced the REDD1 expression leading to mTOR signal pathway inhibition in gastric cancer cells. BP inhibited the in vivo growth of AGS xenograft tumors. These results may provide the basis for a new therapeutic approach toward the treatment of gastric cancer progression.

Related Papers

• → Importance of Wine-Treated Angelica Sinensis Radix in Si Wu Tang, a Traditional Herbal Formula for Treating Womenʼs Ailments(2013)17 cited
• The Comparison of the Contents of Ferulic Acid and Polysaccharide in Angelica Sinensis Oliv. with Lotiform Angelica Sinensis(2006)
• Effect of Continuous Cropping on the Essential Oils of Angelica sinensis (Oliv.) Diels(2009)
• → 药用植物当归研究进展<br>Advances on Traditional Chinese Medicinal Herbs Angelica sinensis(2012)
• → Liquid chromatographic fingerprinting technique for quality control of Angelica sinensis and its preparation(2023)