Myocardial Infarction in Young Women in Relation to Plasma Total Homocysteine, Folate, and a Common Variant in the Methylenetetrahydrofolate Reductase Gene
Circulation1997Vol. 96(2), pp. 412–417
Citations Over TimeTop 1% of 1997 papers
Stephen M. Schwartz, David S. Siscovick, M.R. Malinow, Frits R. Rosendaal, R. Kevin Beverly, David L. Hess, Bruce M. Psaty, W.T. Longstreth, Thomas D. Koepsell, Trivellore E. Raghunathan, Pieter H. Reitsma
Abstract
These data support the hypothesis that elevated plasma tHCY and low plasma folate are risk factors for MI among young women. Although homozygosity for MTHFR T677 is related to increased plasma tHCY and low plasma folate, this genetic characteristic is not a risk factor for MI in this population.
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