HDL (High-Density Lipoprotein) Subclasses, Lipid Content, and Function Trajectories Across the Menopause Transition
Arteriosclerosis Thrombosis and Vascular Biology2020Vol. 41(2), pp. 951–961
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Samar R. El Khoudary, Xirun Chen, Alexis Nasr, J T Billheimer, Maria M. Brooks, Dan McConnell, Trevor J. Orchard, Sybil L. Crawford, Karen A. Matthews, Daniel McConnell
Abstract
Although HDL cholesterol increased over the MT, HDL subclasses and lipid content showed adverse changes. While overall HDL-CEC increased, HDL-CEC per HDL-P declined, consistent with reduced function per particle. Large HDL-P may become less efficient in promoting HDL-CEC during the MT.
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