MicroRNA-210 Controls Mitochondrial Metabolism and Protects Heart Function in Myocardial Infarction
Circulation2022Vol. 145(15), pp. 1140–1153
Citations Over TimeTop 1% of 2022 papers
Abstract
MicroRNA-210 targeting glycerol-3-phosphate dehydrogenase controls mitochondrial bioenergetics and ROS flux and improves cardiac function in a murine model of myocardial infarction in the setting of IR injury. The findings suggest new insights into the mechanisms and therapeutic targets for treatment of ischemic heart disease.
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