Expression of CD34 and L-Selectin on Human Corneal Keratocytes
Investigative Ophthalmology & Visual Science2003Vol. 44(11), pp. 4689–4689
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Annie Joseph, Parwez Hossain, Seema Jham, Rhodri E. Jones, Patrick J. Tighe, Richard S. McIntosh, Harminder S. Dua
Abstract
Normal human corneal keratocytes express all three classes of CD34. The expression of this adhesion molecule on corneal keratocytes suggests that it may have a role in keeping the keratocytes anchored in their microniche, between the collagen lamellae. The positive staining for L-selectin found by immunohistochemistry but not by Western blotting or PCR would indicate the presence of either another ligand from the selectin family or a cross-reactive epitope on corneal keratocytes.
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