Response of Lens Epithelial Cells to Injury: Role of Lumican in Epithelial-Mesenchymal Transition
Investigative Ophthalmology & Visual Science2003Vol. 44(5), pp. 2094–2094
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Shizuya Saika, Takeshi Miyamoto, Sai‐ichi Tanaka, Takeshi Tanaka, Iku Ishida, Yoshitaka Ohnishi, Akira Ooshima, Toshiyuki Ishiwata, Gorô Asano, Tai-ichiro Chikama, Atsushi Shiraishi, Chia‐Yang Liu, Candace W.-C. Kao, Winston W.‐Y. Kao
Abstract
Human capsular opacification contains lumican, and mouse LECs upregulate lumican and alphaSMA in response to injury. Loss of lumican perturbs EMT of mouse LECs.
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