Role of Hypoxia during Normal Retinal Vessel Development and in Experimental Retinopathy of Prematurity
Investigative Ophthalmology & Visual Science2003Vol. 44(7), pp. 3119–3119
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Abstract
(19)F MRS of a perfluorocarbon droplet provides an accurate measure of preretinal vitreous oxygen tension in rats. These data support an important role of physiologic hypoxia in normal retinal circulatory development and raises the possibility that, in experimental ROP, retinal hypoxia is a necessary but not sufficient condition for the development of retinal NV.
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