Effect of Human Cationic Antimicrobial Protein 18 Peptide on Endotoxin-Induced Uveitis in Rats
Investigative Ophthalmology & Visual Science2003Vol. 44(10), pp. 4412–4412
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Kazuhiro Ohgami, Iliyana Ilieva, Kenji Shiratori, Emiko Isogai, Kazuhiko Yoshida, Satoshi Kotake, Tomomi Nishida, Nobuhisa Mizuki, Shigeaki Ohno
Abstract
The present results indicate that hCAP18 peptide suppresses development of EIU. A possible mechanism for the ocular anti-inflammatory effect of hCAP18 peptide is that it suppresses onset of LPS-triggered inflammatory reactions by binding directly to LPS.
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