Oxidative Stress Affects the Junctional Integrity of Retinal Pigment Epithelial Cells
Investigative Ophthalmology & Visual Science2004Vol. 45(2), pp. 675–675
Citations Over TimeTop 10% of 2004 papers
T. A. Bailey, Naheed Kanuga, Ignacio A. Romero, John Greenwood, Philip J. Luthert, Michael E. Cheetham
Abstract
Increased resistance to chronic oxidative stress with differentiation in ARPE-19 cells correlated with higher steady state levels of Hsp27 and Hsp70. Oxidative stress disrupted RPE cell junction and barrier integrity, which may contribute to the pathogenesis of diseases related to RPE through disruption of the blood-retinal barrier.
Related Papers
- → Hsp27 negatively regulates cell death by interacting with cytochrome c(2000)980 cited
- → Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27(1995)277 cited
- → Doxorubicin-induced cardiotoxicity: direct correlation of cardiac fibroblast and H9c2 cell survival and aconitase activity with heat shock protein 27(2007)71 cited
- → Light‐emitting diode irradiation using 660 nm promotes human fibroblast HSP90 expression and changes cellular activity and morphology(2019)19 cited
- 類澱粉前驅蛋白過表現Neuro 2a細胞及在初代神經細胞中內生性β-amyloid對粒線體產生的影響及熱休克蛋白的表現(2007)